Thyroxin is the main hormone of the thyroid gland and a participant in many processes inside the body. It stimulates mental activity, motor and mental activity, metabolism, glycolysis, lipolysis. Increases blood glucose levels. Inhibits the formation and deposition of fat. All this is important for losing weight: one of the consequences of disrupting its functioning is the rapid and uncontrolled weight gain. To compensate for its deficiency, prescribe buy Synthroid online, a thyroid-stimulating hormone drug.
The main active ingredient is Synthroid sodium (its Latin name is levothyroxine sodium). This is the sodium salt obtained by synthetic means. It partially biotransformed in the kidneys and liver, turning into liothyronine (T 3 ), and actively stimulates metabolic processes. In the composition of one tablet can be 25, 50, 75,100, 150 or 200 μg of the main active ingredient.
The list of auxiliary components depends on the manufacturer.
Synthroid sodium is found in concentrations of 50, 75, 100, 150 μg. Additionally in the composition appear:
- microcrystalline cellulose;
- calcium phosphate;
- sodium starch glycolate;
- long chain partial glycerides.
The number of tablets in the package is from 50 to 150.
The concentration of the active substance is represented by a wide range – from 25 to 200 μg. Additional composition is not specified. The package of 50 tablets.
The active substance is 25, 50 and 100 μg. Additionally included are:
- potato starch;
- lactose monohydrate;
- powdered sugar;
- basic magnesium carbonate;
- magnesium stearate;
- low molecular weight medical polyvinylpyrrolidone.
Packs of 50 and 100 tablets.
Only 1 variant of concentration of Synthroid and sodium is 100 mkg. Composition complement:
- milk sugar;
- magnesium stearate.
The package contains 100 tablets.
The main active ingredient is 50 and 100 µg. Additional components in the composition of the tablets are not specified. There are packs of 50 and 100 pcs.
In pharmacies, you can buy Synthroid and other manufacturers: 1A Pharma, Hexal, Jod Winthrop, etc.
Weight loss mechanism
What exactly is beneficial for thyroxine for weight loss? According to studies, it is not only superior to its effectiveness. fat-burning dietary supplements, but also drugs of this nature. It has a complex effect on the body, aimed specifically at those processes that contribute to intensive weight loss:
- speeds up metabolism;
- enhances heat production, being thermogenic;
- increases calorie consumption;
- stimulates the central nervous system, prolonging the state of wakefulness and activity, increases efficiency, reduces the need for sleep, which allows you to use it as an energy drink for sports;
- suppresses appetite
Availability and high performance have made thyroxine popular with bodybuilders and anyone who dreams of losing weight fast. It is, indeed, one of the few weight loss remedies that works. However, not for a moment do not forget that this is not a harmless dietary supplement, but a powerful hormonal drug.
According to the Law, thyroxine should be dispensed in pharmacies by prescription, since it has a strictly defined range of indications and is a powerful hormone medication. However, in reality, in many pharmacies, it is sold freely available. In medicine, it is used to treat various diseases:
- euthyroid hyperplasia of the thyroid gland;
- cerebral pituitary diseases;
- recurrent diffuse euthyroid and nodular goiter, if thyroid resection was performed;
- Graves and Hashimoto diseases;
- papillary and follicular carcinoma;
- thyroid cancer.
Those who decide to lose weight with Synthroid should be reassured by the fact that the list of indications includes obesity. However, the drug will be effective only if the BMI will significantly exceed the norm. If you plan to lose up to 5 kg, you should not resort to such a powerful tool.
If the thyroid gland is working properly, drinking Synthroid does not make sense, otherwise there will be an overabundance of this hormone in the body. Therefore, experts recommend taking a blood test, which will show its level. For men, the indicator is 60-135 nmol / l (+/- small deviations dictated by the individual characteristics of the organism), for women this corridor is 70-140 nmol / l.
Absolute contraindications for taking Synthroid:
- individual intolerance of the main active ingredient;
- acute myocardial infarction;
- inflammation of the heart muscle;
- hereditary galactosemia, lactase deficiency, impaired intestinal absorption syndrome.
Relative contraindications that require mandatory prior consultation with a doctor:
- cardiovascular diseases: history of myocardial infarction, ischemia, angina pectoris, atherosclerosis, arrhythmia, hypertension;
- severe hypothyroidism;
Non-compliance with contraindications and incorrectly chosen dose of thyroxine are fraught with serious health complications. This is perhaps the only, but significant drawback of this drug, forcing many to refuse it.
Frequently observed side effects:
- unexplained anxiety, tremor, headaches, insomnia;
- heart problems: arrhythmia, angina, extrasystole, tachycardia;
- vomiting, diarrhea;
- skin rash, itching, angioedema;
- menstrual disorders;
- hyperhidrosis, hyperthermia, feeling of heat, increased weakness, muscle cramps;
- allergic reactions: bronchospasms, urticaria, laryngeal edema, anaphylactic shock.
When these symptoms appear, you must either reduce the dose or completely stop taking it for 4-5 days. After their disappearance, you can continue to take pills, but with great care, only after consulting a doctor and starting with the minimum doses.
Those who take Synthroid for weight loss, most often faced with uncontrolled anxiety and an irrational sense of fear that cause a strong heartbeat. Bodybuilders who use this drug on an ongoing basis are advised to combine this remedy with β-adrenoreceptor antagonists (metoprolol, atenolol, betaxolol) to eliminate these side effects. This combination normalizes heart rhythm, reduces the risk of other side effects.
The whole danger of the unjustified use of Synthroid can be imagined, given the fact that there were several cases of sudden death due to a malfunction of cardiac activity in people who used the drug for too long a time and exceeded the recommended dosage.
Instructions for use
When purchasing Synthroid for weight loss, keep in mind that in this case, the regimen will be significantly different from the one prescribed in the instructions.
For beginners, the dosage should not exceed 50 mg per day, and it is better to divide it by 2 times. It is necessary to take both pills in the morning: for example, after breakfast and after lunch. Gradually, the daily rate is increased to 300 micrograms, which is recommended to be taken in 3 doses, but not later than six in the evening, in order not to provoke insomnia.
Slimming with Synthroid-50
- The first 4 days – 1 tablet once a day (or break it into halves and drink in 2 doses).
- The next 2 days – 2 tablets.
- Another 2 days – 3.
- Further – on 4.
A week before the end of the drug intake, reduce the dosage in the reverse order.
Slimming with Synthroid-100
- The first 4 days – 1 (once a day) or ½ (twice) tablets.
- From 5 to 7 – 2 tablets.
- From 8 until the end of the course of weight loss – by 3.
Along with Synthroid, it is recommended to start drinking β-blockers. However, these are no less powerful drugs, the use of which should also be coordinated with the doctor. Moreover, their dosage depends on the individual parameter – pulse rate. It is necessary that at the time of losing weight, this figure did not rise above 70 beats per minute and did not fall below 60. The only way to achieve efficiency from this remedy.
If diarrhea has started on the background of taking Synthroid, digestion can be normalized with Loperamide (2 capsules per day).
The course of weight loss is from 1 to 2 months. It is necessary to complete the administration of Synthroid as smoothly as they started, gradually reducing the dosage. The interval between courses should not be less than 1 month.
This hormonal agent can block or enhance the effect of certain drugs. Therefore, if you really need to reduce weight and use other pills at the same time, keep a list of those with which Synthroid sodium is incompatible:
- anticoagulants (increased risk of hemorrhage in the gastrointestinal tract and brain);
- protease and tyrosine kinase inhibitors;
- Kolestiramin, Kolestipol;
- preparations containing aluminum, iron, iodine, calcium carbonate;
- lanthanum carbonate, Sevelamer;
- proguanil / chloroquine, sertraline;
- carbamazepine, barbiturates;
- furosemide, salicylates, clofibrate;
- glucocorticosteroids, propylthiouracil;
If a woman takes Synthroid at the same time as hormonal contraceptives containing estrogen, you will need to take an overdose of Synthroid as well. This also applies to those who have been prescribed hormone replacement therapy in postmenopausal women.
Store in a dry place, away from sunlight, at temperatures up to 25 ° C. On average, the shelf life is not more than 3 years.
Compatibility with alcohol
Many wonder if Synthroid is compatible with alcohol. The question is not quite appropriate, since any weight loss excludes the use of such drinks. If we are talking about 1-2 glasses of wine, they will not affect the intake of this drug. However, against the background of alcohol abuse, the work of the liver and the heart is deteriorating, which can provoke complications. Therefore, it is better not to risk it. Although the instructions currently not covered by any drug manufacturer.
During pregnancy and lactation
During pregnancy and lactation, it is allowed to take Synthroid in order to lose weight. But if the safety of a drug for a newborn is scientifically proven, since the hormone practically does not penetrate into breast milk, then its effect on the fetal development of the fetus has not yet been thoroughly studied. In this regard, experts warn future moms to lose weight in this way.
How to drink
Half an hour before one of the main meals and drink plenty of ordinary water. No need to experiment with milk and juices: they reduce the absorption of hormonal drugs in the blood. You can not abruptly stop its use, unless it threatens the health in the form of pronounced side effects. Without a doctor’s recommendation and testing for hormones, it is undesirable to drink pills, otherwise a hormone oversupply can provoke an even greater weight gain.
How to increase efficiency
Many who have experience with weight loss with Synthroid, argue that this is one of the few drugs that promote weight loss without dieting and exercise. In the first week of its reception it is quite possible, because the body will react violently to such hormonal changes. According to reviews, during this time you can lose 3-4 kg. But then in most cases the mark on the scales remains unchanged, although you will exactly follow the regimen.
In order to continue losing weight, you still have to limit yourself to nutrition and load the body physically. No lipolysis, even under the influence of thyroxin, will not proceed normally, if fats prevail in the diet. Diets are not necessary to follow, but to exclude from the menu fast food, fried and fatty meals, simple carbohydrates is desirable.
As for training, here it is worth reading reviews of experienced bodybuilders. They no longer perceive these pills as a drug for the treatment of diseases associated with the thyroid gland. For them, this is a complete sports nutrition that increases stamina and accelerates metabolism. It is not necessary to work with iron after them: any classes will improve the final result.
With proper nutrition and regular (not even intensive) training, taking Synthroid can reduce weight to 10 kg in 2 months.
There are no better or worse among them – all of them are approximately the same in composition, pharmacological properties and regimens. By popularity in terms of losing weight with Thyroxine competes Eutiroks. Other trademarks are less in demand.
Before organizing weight loss using Synthroid, you need to carefully weigh the pros and cons. If there is obesity and the doctor’s permission to receive it, doubts are eliminated. In other cases, keep in mind that any intervention in the hormones without medical indications may result in irreversible complications that can worsen the quality of later life.