IDEAL SLEEPING CONDITIONS FOR MAXIMUM DEVELOPMENT OF TESTOSTERONE

WHAT SHOULD WE MAKE FOR THE MAXIMUM DEVELOPMENT OF THE TESTOSTERONE WHILE SLEEPING?

DURATION OF SLEEP

Sleep for 6-8 hours a day. This is just as much as necessary for sleep, and not at all the amount of time you spend in bed.

A deep sleep is the time of testosterone. Scientists who study sleep speak of its five stages, the so-called sleep architecture. Basically during sleep you go through the hour and a half cycles. The last 15 minutes of each cycle are restorative portions of deep sleep. With deep sleep our eyes move quickly. It is then that we see dreams; As if our eyes quickly look through the films projected from within.

Deep sleep is also part of the cycle with the maximum production of testosterone. It is at these intervals that men develop erections lasting an average of 15 minutes and repeating throughout the night at intervals of 1.5 hours. Therefore, men wake up (should wake up) with an erection (see “What is the lack of an erection in the morning?”). The quality and duration of deep sleep depends a lot in the physical and emotional state: resistance to stress, internal energy, including the production of sperm, strengthening bones, the emergence of ambition. In order to make a deep sleep much better, carefully follow the recommendations below.

EXCLUDE NOISE INTERFERENCE

The maximum production of testosterone occurs with absolute silence. If there are any irritating factors (any noise), testosterone production does not happen so intensively.

Use Earplugs. Sleep in absolute silence. Perhaps, you think that your bedroom is relatively free of noise. But in order to optimize sleep, it is necessary to go to extreme measures and use earplugs.

Use only high-quality ear plugs made of lightweight rubberized material. It easily bends and takes the shape of your ear. Such you will find in most pharmacies. Do not put anything home-made into your ear.

Using ear plugs, you can not hear the alarm bell, since you will sleep a deep sleep. Make sure your alarm is ringing loud enough to hear it.

EXCLUDE LIGHT DIFFUSERS

Electric lighting is a relatively young invention. For many centuries a man lay down when the sun was setting, and rose with the rising. Now we can turn on the bright light at any time of the day. Our body has to get used to, and this violates the internal rhythms. Since our life is no longer connected with sunrise and sunset, the body suffers from excessive lighting. It is beneficial for production and economy, but absolutely not beneficial for quality sleep.

At night, most houses are penetrated by moonlight, street lighting and light from nearby houses. There are many curtains, curtains and blinds capable of reducing the penetration of light into your home. However, the most effective technique is a mask for sleeping.

Wear a mask for sleep. There is a difference between dark and absolutely black (like pitch). Sleep in total darkness. Use for this purpose an opaque mask for sleep (you can purchase it in any pharmacy).

LET THE LOWER HALF OF YOUR BODY WILL BE NUDE DURING THE SLEEP

A mandatory condition is the optimal temperature of male testes (3 ° C less than body temperature). For this, a man during sleep should be without panties, preferably not covering the lower body or covering himself with a warm blanket (sheet).

To sleep naked is not very convenient in a society of children. Limit the children from the bedroom, keep clothes close at hand or attach a fantasy and find another way out of the situation.

SLIGHTLY CHECK THE ROOM BEFORE SPACE

Keep the room at a temperature of 18-21 ° C and discard thick blankets. If at night you wake up from the fact that you are hot or you are sweating and throwing the blanket on the floor, it means that either the room or the blanket is too warm. In order to accurately measure the temperature in the room, get a reliable electronic thermometer.

Let your room be cool enough to make you feel comfortable.

Why sleep in a cool room? Let’s say that the temperature is too high (for example, 27 ° C). Your body, in order to cool, will sweat all night long. This means that more warm blood will be delivered to the surface layer of the skin, taking out the internal heat of the body outside. In this case, the blood flows from the warm, internal area, to the periphery. You take blood from the gland, which reduces its productivity.

And now imagine that the temperature is too low, say 10 ° C. In this scenario, your body thinks as follows: “It’s too cold and you need to sacrifice such less important areas as skin, fingers, legs, ears, etc. It is necessary to direct blood inside, to the most vital objects – the brain, the heart, And other organs, including the kidneys and glands. ” This is exactly what you need.

By cooling the room, you direct blood to important organs, including glands, using the natural ability of the body to direct blood flows to various parts of it. This ability of our body saves us life, when blood pressure rises in severe bleeding, and loss of blood decreases when a limb is lost.

Obviously, it is difficult to expect a good sleep at a temperature of 10 ° C. However, you can achieve the necessary redistribution of resources in the body at a comfortable temperature of 18 to 21 ° C. Stay cool.

FOLLOW THE BASIC PRINCIPLES

  • No caffeine.
  • Do not overeat.
  • No tiring exercises (sex does not count).
  • No alcohol.
  • Do not smoke.
  • Do not drink much before bed.

Caffeine, tedious exercises and nicotine stimulate the nervous system and drive away sleep. When overeating, blood concentrates mainly on the intestines, instead of serving the genitourinary system. In reality, this destroys the quality sleep system, known as the sleep architecture.

Similarly, if you drink a lot of fluids 2-3 hours before bedtime, you can be sure that in the middle of the night you will have to wake up and go to the toilet.

USE A COMFORTABLE MATTRESS AND PILLOW

If you wake up with a poor state of health, depressed and not rested, this indicates a decrease in hormone production at night. A good sleep in a good bed contributes to the production of testosterone, which restores and maintains the entire body. Do not undermine the capabilities of your testosterone by spending a third of your life on a too soft, cheap and old bed.

Invest in the purchase of good, durable and comfortable mattresses and pillows. People who work in the hospitality industry understand this and take pride in the quality of their beds. They invest a lot of money in the purchase of resilient and comfortable mattresses, which can even have special thickening, replacing the pillow. It is not necessary to buy a state-of-the-art heated mattress, which vibrates and bends at different angles, it is enough just to choose a reliable brand mattress that will last you a long time.

Sleep on a bed of the appropriate size. If your partner often bothers you with “acrobatic tricks”, get a big bed. Pets and children also need to sleep separately from you.

Having created all the necessary conditions for sleep, you will provide yourself a good basis for the development of male hormones.

HOW TO IMPROVE THE QUALITY OF THE SPERM

HEALTH INDICATORS OF SCHERMOTAZOIDS

Amount. The normal indicator of the number of sperm per 1 ml of sperm is about 20 million. But this is not the most important indicator, since only one sperm is needed to fertilize the egg.

Quality. A normal indicator of the quality of spermatozoa is not more than 50% of spermatozoa with a pathology of their total number, i.e. The number of healthy spermatozoa (with an oval head and long tail) should be greater than or equal to half of the total number of spermatozoa.

Mobility. In healthy semen, at least half of the spermatozoa should be mobile. Even in a completely healthy sperm, immobile sperm are present, and this is normal.

WHAT DOES NEGATIVE INFLUENCE THE QUALITY OF THE SURFACE?

BAD HABITS

Alcohol, smoking, taking drugs reduces the concentration of spermatozoa. Long-term use can lead to infertility. Therefore, we must abandon bad habits, at least temporarily (3-4 months before conception). Just rejection of bad habits, can become a decisive factor in the normalization of spermatogenesis.

DEPRESSION AND STRESS

Nature arranged so that the birth of the offspring should take place in the most comfortable environment, in order to increase the chances of helpless progeny to survive. A stress is a signal to the body about unfavorable conditions. As a result, the function of childbirth is depressed.

Stress in men is a proven factor in reducing sex hormones and the number of sperm in the ejaculate.

Treatment of stress should be based on the elimination of the cause of the illness and psychotherapy, but not drug treatment, tk. One of the side effects of various antidepressants is a deterioration in the quality of sperm and sexual function in general.

EXCESS WEIGHT

Excess body weight is accompanied by an increased conversion of testosterone to estrogen, which primarily inhibits sexual function (see the relationship between obesity and testosterone). The pathological condition is the length of the circumference of the waist of a man greater than 94 cm.

OVERHAGING OF EGGS

It has long been known that the temperature of the testicles should be less than the temperature of the body, for this they are taken out. A tight, dense male underwear that presses the testicles to the body, creates unnecessary heating and prevents the development of sperm and testosterone. Men with infertility should avoid frequent baths, paired baths, taking hot baths.

Long stay in a sitting position also leads to overheating, besides, with constant sedentary work, blood circulation to the pelvic region is disturbed, which leads to a decrease in potency.

In the risk zone:

  • Foundry workers, furnace workers;
  • Office workers, whose profession assumes constant sitting;
  • Drivers, truckers.

To normalize blood circulation, you can do exercises for the pubic-coccygeal muscle, without even having to get up from the chair, i.e. It is convenient to do in any place (at work, transport, etc.).

RADIATION OF MOBILE TELEPHONES AND NOTEBOOKS

A lot of men wear mobile phones in their front pockets, not suspecting that the phone emits electromagnetic waves that affect the quality of the sperm. If possible, remove the phone away from the testicles.

Another common mistake of men is to work with a laptop on your lap. This causes the testes to overheat. Work with a laptop at the table, then it will not have a detrimental effect on the quality of sperm.

ECOLOGY AND CONDITIONS OF LABOR

The polluted air of large megacities reduces the speed of movement of spermatozoa. Permanent inhalation of vapors of toxic substances such as gasoline, paint, varnish, etc. Also affect the quality of sperm not for the better. Work with industrial and chemical drugs can cause temporary infertility.

Occupations of men who are at risk:

  • Workers of metallurgical and chemical industry;
  • Painters, decorators, finishers;
  • Employees of the furniture industry (paint and varnish work);
  • Workers in the agricultural sector (working with pesticides);
  • Builders;
  • Auto mechanics, the worker of refueling, washing;
  • Workers smoking smokestacks of the food industry.

In this case, you need to remember about milk, the molecules of which are combined with toxic compounds in the body, thereby neutralizing them. Selenium is another helper in the fight against poor ecology and working conditions. It has a detoxification effect on the body.

INFECTIOUS DISEASES OF UROLINE SYSTEM AND STDs

As in the case of a testicle trauma, an immune reaction against spermatozoa occurs, i. E. Antibodies, developed by the body to protect against infection, attack their own spermatozoa. To diagnose the disease, you will need to take tests and consult a urologist.

Adhere to these recommendations, and the chances of a healthy offspring will increase.

IMPROVE THE QUALITY OF THE SURFACE

FOOD

Nutrition plays a key role in the formation of healthy spermatozoa. Briefly, the rejection of synthetic products, fully formed as a result of human activity, and increased consumption of products created by nature itself (fruits, vegetables, herbs, cereals) will positively affect the function of spermatogenesis.

We include in the diet:

  • Vitamins

Vitamin E is one of the most important vitamins responsible for the fertility of a man and his sexual function. The minimum daily dose of vitamin E for men is 10-15 mg, but for medicinal purposes, the dose may well be increased by 2-3 times. Especially to get a daily dose of vitamin E is very easy: 50-100 g of nuts (walnut, almonds, hazelnuts).

Vitamin C is a powerful antioxidant for our body. The daily dose of vitamin C for men is 100 mg. Exceeding the daily dose will not harm Vitamin C is a water-soluble vitamin, therefore surpluses will be excreted from the body together with urine. The daily requirement is covered: 20 g of dog rose, 50 g of red pepper, 100 g of parsley or dill, 120 g of kiwi, 200-300 g of citrus.

Folic acid (vitamin B9) is necessary not only for women during pregnancy, but also for men during conception planning. Although there is no confirmed data on the effectiveness of folic acid in increasing fertility.

L-carnitine (vitamin B11) and arginine. Potentially useful for increasing fertility in men. Contained in products of animal origin, nuts, pumpkin seeds.

  • Minerals

The primary importance in spermatogenesis and the production of sex hormones are zinc and selenium. Daily doses for men are 15 mg and 70-100 μg, respectively. These microelements can be found mainly in seafood, nuts (pistachios for replenishing selenium). There is also a complex preparation of selenium and zinc – Selzinc.

Also pay attention to products that improve blood circulation.

Exclude (severely restrict) from the diet:

  • Fatty foods.
  • Baking, baking.
  • Sweets.
  • Fast food.
  • Smoked products.

LESSON ON PHYSICAL CULTURE

Active way of life and sports have not harmed anyone yet. Only it is necessary to adhere to moderate loads, do not play sports every day – 3-4 times a week will be quite enough.

Adhere to these recommendations, and the chances of conceiving a healthy offspring will increase many-fold.

How to accelerate the growth of the beard in home conditions?

Why does one have a beard, and do not have others?

There is simply no exact answer to this question, but there are several assumptions on this topic:

1. Heredity and genetics. Perhaps, this is the most obvious factor, why some people have an abundant growth of hair on their face, while others do not. But, some can exclaim: “After all, my father has a thick stubble, but I do not!”. The presence of vegetation on the face of the father does not mean that it should appear with you. Since genes are transmitted non-linearly, and you are not a complete copy of the father, it means that the gene responsible for the growth of facial hair can contain other information. But, nevertheless, the presence of dense bristles in the father is a good predisposing factor for the growth of your beard.

2. Your time for growing your beard has not yet come. If you are under 18 years old, then judge what vegetation on the face will be in the future still early. Yes, many peers can already have thick bristles, but this should not be an indicator. Everyone has their own time for puberty and maybe it has not come to you yet!

3. Your body does not have enough strength to form a new hairline. The reason for this may be:

  • Chronic diseases, weakening the body;
  • Incorrect and unbalanced nutrition;
  • Bad habits;
  • Stress, depression;
  • A constant state of overtraining;

and other.

Analyze the state of your health – if it is unsatisfactory, it can be the reason for the lack of hair growth on the face.

4. Low level of sex hormones. Since the beard is a masculine sign, for its appearance meets testosterone – the main sex hormone of a man. Insufficient level of testosterone may be the reason for the lack of vegetation on the face and body. But, the presence of a normal testosterone level does not yet guarantee to you a thick beard, since the effect of sex hormones can differ for two different individuals. For example, with the same level of testosterone in men, there can be absolutely different intensity and density of growth of the beard. This depends on the sensitivity of the receptors to testosterone and other genetic features.

HOW TO INCREASE BROAD GROWTH?

These recommendations are equally effective both for stimulating the growth of already existing hair, and for activating the growth of new ones. To achieve tangible results, an integrated approach is required, which implies:

  • Natural methods of internal stimulation.
  • Hygienic and cosmetic procedures for external stimulation.
  • Use of special tools.

1. NATURAL WAYS OF INTERNAL BEAUTY GROWTH STIMULATION

INSPECTION OF THE TESTOSTERONE

Indeed, a low level of male sex hormones (androgens) may be the cause of poor vegetation on the body and face. However, to begin with it is necessary to be convinced, that the problem really is in hormones. The most reliable way to know your testosterone level is to take a blood test. It can be done on a fee basis in any of the clinics that provide these services.

If the test for total testosterone showed poor results (see testosterone levels), it is necessary to visit the endocrinologist and understand the causes of the decrease in androgens. The doctor will prescribe the necessary course of treatment to restore the normal level of hormones. After that, you can expect to increase the growth of hair on the body and face.

For those who independently decided to increase their testosterone, we advise reading:

– How to increase testosterone naturally?

– Products that raise testosterone

– Simple exercises to increase testosterone

– And other articles from the section “Testosterone and hormones”

HEALTHY FOOD

In the concept of “healthy nutrition” we will include not only food useful for our body, but also products containing the necessary substances for health and hair growth. To form hair, proteins, amino acids, certain vitamins and minerals are needed. Replenishment of these substances can significantly improve the growth and formation of hair.

Vitamin A, C, E – these vitamins are needed in any case to maintain the normal function of all body systems:

  • Vitamin A – is necessary for the growth of the body, strengthens the hair, preventing their loss and fragility. Contained in carrots, broccoli, butter, cheese, sea kale.
  • Vitamin C – is responsible for immunity, improves nutrition of the hair. Contained in citrus (orange, lemon), pepper, kiwi, cabbage (broccoli, colored, red).
  • Vitamin E – improves blood circulation and delivery of nutrients to hair follicles. Contained in nuts, dried apricots, prunes, oatmeal.

Vitamins of group B – very important group of vitamins for health of hair. Of particular importance are:

  • Vitamin B7 (biotin, vitamin H) is perhaps the most important vitamin for hair health. Biotin is synthesized in our intestines in quantities sufficient for the body (under conditions of normal functioning of the gastrointestinal tract), and is also found in many food products. The most biotin in the chicken egg, oatmeal, peas, nuts.
  • Vitamin B9 (folic acid). Like biotin, folic acid can be synthesized by the intestinal microflora. It is useful not only for the health of hair, but also for improving reproductive function – there are data on the positive effect of vitamin B9 on the number of spermatozoa in men. A lot of folic acid is found in nuts (peanuts, walnuts, almonds, hazelnuts), spinach, lettuce, beans, liver.

Minerals are an auxiliary building material for the hair, so you can not do without them if you want to grow a magnificent beard. The most useful of them are:

  • Zinc is the most important microelement for the male body. Really! A sufficient amount of zinc in the diet is able to solve most of the problems with men’s health (for more details on the role of zinc read here).
  • Calcium is necessary for maintaining the density of bones and the structure of the hair. A lot of calcium is found in dairy products (cheese, cheese, milk, cottage cheese), nuts, sesame, peas, oatmeal.
  • Iron – is necessary for hematopoiesis and strengthening of hair. Contained in nuts, liver, buckwheat.

Based on all of the above, we will compile a list of products useful for growing a beard:

  • Fruits and vegetables (cabbage of all sorts, pepper, carrots, beets, orange, kiwi);
  • Nuts;
  • Fish and seafood;
  • Greens and leafy vegetables (spinach, lettuce, dill, parsley, garlic);
  • Meat (chicken breast – a source of easily digestible protein, B vitamins, beef – a source of zinc, B vitamins);
  • The liver (chicken, beef, pork) is a source of zinc, and other vitamins;
  • Eggs;
  • Legumes (beans, peas);
  • Kashi (oatmeal, buckwheat);
  • Dairy products (cheese, brynza, cottage cheese) – a source of calcium, protein.

From what products it is necessary to refuse:

  • Sweet;
  • Salt (read about how much salt a man needs);
  • Caffeine;
  • Fast food.

LESSONS WITH STRENGTHENING

Many men note that after they started going to the gym, the growth of facial hair accelerated. For many, this contributed to the launch of new hair growth. There is nothing surprising, since exercises with weights increase the level of testosterone. And to achieve from training the maximum increase in sex hormones, you should follow some recommendations:

  • Be sure to perform such exercises as squatting, deadlift, bench press, as it is the basic exercises that contribute to the maximum production of testosterone. Doing only isolated exercises on small muscle groups can not achieve a significant increase in the level of androgens.
  • Weight of burdens should be selected in such a way that for the approach it was possible to perform a maximum of 8-10 repetitions. The last repetition should cause maximum effort.
  • The duration of training should not exceed an hour. Occupations with weights increase the level of anabolic hormones (testosterone, growth hormone) responsible for muscle growth. After an hour of study, the situation changes to the opposite and catabolic hormones (cortisol), responsible for the destruction of muscles, begin to be synthesized into the blood.
  • Do not allow overtraining. The state of overtraining reduces the level of sex hormones. It is important to remember that muscles grow during rest, so the recovery process is as important as the training process. Train no more than 2-3 times a week, cycling the load on different muscle groups (so-called split-workouts).

2. HYGIENIC PROCEDURES FOR EXTERNAL STIMULATION OF HAIR GROWTH

It is necessary to stimulate the growth of the beard not only by internal factors, but also by external factors. Hair growth in many ways depends on the purity and condition of the skin. Here are some tips for future bearded men:

  • Keep the skin clean. For this, you do not need to use various means for washing. There used to be a lot of bearded men, did they all use tonics? It is difficult to imagine a peasant who smears himself with lotion every morning! In their arsenal there was only simple cold water. It is cold water, as it additionally stimulates blood circulation. So, in order to keep your face clean, thoroughly wash with cold water 2-3 times a day or as it gets soiled.
  • Use burdock oil. The method of application is simple: you need to take burdock oil (preferably slightly warmed) and rub it into the skin. After holding no more than an hour you can wash it off.The best effect is achieved if the burdock oil is mixed with red pepper – in addition to feeding the hair, the blood circulation to the hair bulb is strengthened. However, you need to be careful if you use pepper and do not overdo it with its addition. Otherwise, you can cause a strong red face. This procedure should be performed 2-3 times a week with the addition of pepper or every day only with burdock oil. Burdock oil can be bought at any pharmacy (see Figure 2). Its cost is about 60-80 rubles.
  • Another folk remedy: mix eucalyptus oil with water in a proportion of at least 1: 4 (1 part oil to 4 parts water) and apply to the skin with a cotton swab. After the procedure, rinse thoroughly with a skin without residues.

3. USE OF SPECIAL FUNDS

Minoxidil is the active substance of preparations for improving hair growth. Traditionally, minoxidil was used to activate hair growth on the head. A little later it was revealed that the drug also has a significant effect in activating the growth of facial hair.

THE PRINCIPLE OF WORK OF MINISTRY

The principle of minoxidil is to expand the blood vessels and increase blood microcirculation, which positively affects the development of hair follicles. This contributes not only to the appearance of a new hair, but also to the fact that the hair of the hair, getting increased nutrition, develops into a thermal hair – that is, hard and long.

WHAT CAN YOU CALCULATE?

Minoxidil – an effective tool for accelerating the growth of the beard, but still not a “magic pill”. The final result of the drug will depend on your genetic characteristics and the time of therapy. So, some people can have a noticeable result within a month after the beginning of the course, while others can only see the first results in a few months. Judging by the reports of people using minoxidil, the effective time for therapy is about 1 year.

SELECTION OF PREPARATION OF MINOSPHERE

The choice of the drug is determined primarily by the percentage of minoxidil. There are drugs with 2%, 5%, 10% and a large content of minicidal. We are interested in funds with a 5% content of minoxidil, since 2% drugs do not have sufficient efficacy, and 10% or more are too aggressive.

The form of the release of the means also matters. The most convenient form of the drug is a liquid spray, since in this case it is easiest to keep the dosage.

Xenical in the complex therapy of metabolic syndrome

Interest in the metabolic syndrome in recent years has increased dramatically from various specialists, due to the discovery of subtle molecular mechanisms of interaction of insulin and other factors in various target tissues. G.M. Reaven [5] associates the development of clinical signs of this complex syndrome with insulin resistance, so many suggest the name of the disease – “insulin resistance syndrome”. Indeed, numerous studies [1, 2, 4] proved the presence of hyperinsulinemia, as a compensatory state of the organism in response to insulin resistance. Insulin resistance is the disturbed sensitivity of peripheral tissues (liver, muscles, adipose tissue, etc.) to insulin. Insulin resistance is an inherited condition. The genetic predisposition to insulin resistance is associated with a gene mutation:

  • Insulin receptor substrate I (insulin receptor tyrosine kinase),
  • Glycogen synthase,
  • Glucose transporters II or IV,
  • Hexokinase II,
  • Protein binding the FFA (FABP-II).

At the same time, a hypothesis is advanced according to which insulin resistance is not the cause of the development of this syndrome, but also its one component [4]. The author came to this conclusion on the basis of studying the prevalence of components of the metabolic syndrome in different ethnic groups (black, white population of the USA and Americans of Mexican origin). Analysis of the data obtained suggested the presence of a different genetic factor in the etiology of the metabolic syndrome. Such a hypothetical factor was called “factor Z”, which, interacting with insulin sensitive tissues, endothelium, regulating system of arterial pressure and lipid and lipoprotein exchange, causes, respectively, insulin resistance, atherosclerosis, arterial hypertension, dyslipidemia.

The WHO working group constituting the components of the metabolic syndrome recognized the following symptom complex (1998): visceral (abdominal) obesity, insulin resistance, hyperinsulinemia, impaired glucose tolerance (STH) or type 2 diabetes, arterial hypertension, dyslipidemia, hemostasis disorders, hyperuricemia, microalbuminemia.

The clinical sign of insulin resistance is considered to be the abdominal type of obesity, in which the ratio of the waist to the hip volume exceeds 0.95 in men and 0.85 in women.

The developed therapeutic approach to the treatment of the metabolic syndrome has not been found to date. As a rule, antidiabetic therapy occupies a central place in treatment activities. In the fight against insulin resistance in clinical practice, metformin is widely used in an individually selected dosage. When metformin is ineffective, its combination with sulfonylurea preparations, a-glycosidase inhibitors or nonsulfonylurea secretinogens is used. In complex therapy, hypolipidemic and antihypertensive drugs are recommended, along with diet therapy. However, the fact of the close dependence of insulin resistance on the degree of obesity is known. According to Amos et al. [3], insulin resistance is associated, more likely, with obesity than with diabetes mellitus. Therefore, an urgent requirement is weight reduction in patients with metabolic syndrome. A decrease in body weight of only 5% of the initial weight leads to improved glycemic control, lower blood pressure, improved lipid profile, and a 20% reduction in the risk of premature death.

Given the presence of insulin resistance and, as a consequence, hyperinsulinemia – antilipolytic factor, in the metabolic syndrome, it is natural to assume the difficulty of reducing weight in this category of patients. The presence of arterial hypertension in these patients is an obstacle for the appointment of anorektiky, oppressing appetite by inhibiting the reverse neuronal capture of catecholamines from the intersynaptic gap.

Among the drugs that contribute to weight loss, a special place belongs to orlistat (Xenical Online) – a drug that does not have a systemic effect, acting inhibitory to the gastrointestinal lipase. Xenical has a high lipophilicity and is readily soluble in fats. Due to this, getting into the body with food containing fats, Xenical mingles with drops of fat in the stomach, blocks the active center of the lipase molecule, not allowing the enzyme to split fats (triglycerides). Unclosed triglycerides can not enter the blood and are excreted with feces.

Suppressing the activity of gastrointestinal lipases reduces the absorption of fats, which creates a deficit of energy and helps to reduce body weight. Simultaneously, the number of free fatty acids and monoglycerides in the lumen of the gut decreases, which reduces the solubility and subsequent absorption of cholesterol, contributing to the reduction of hypercholesterolemia. In a placebo-controlled study of 52 weeks duration in patients with diabetes mellitus and visceral obesity (metabolic syndrome), when Xenical was used at a dose of 120 mg 3 times a day, the body weight was reduced by 6.2% from the baseline (Figure 1), at 4.3% In the placebo group (p <0.001). The use of Xenical in patients with metabolic syndrome contributes to the compensation of carbohydrate metabolism (by the end of 1 year of treatment a good SD compensation was achieved in 67% of patients, compared with 31% on a diet). A similar trend was observed and at the end of 2 years of treatment (Figure 2). At the same time, the daily requirement for oral hypoglycemic drugs in patients receiving Xenical decreased by 23%, compared with 9% in patients on a diet (Figure 3). Treatment with Xenical was accompanied by a decrease in insulin levels by 18% (8.7% on a diet). In cases of a metabolic syndrome with impaired tolerance to carbohydrates, a two-year therapy with Xenical reduced the risk of NTG and type 2 diabetes (Fig. 4). The study of the lipid profile showed a significant decrease in the level of cholesterol and lipoprotein compared to placebo (Table 1). After 1 year of Xenical therapy, the diastolic blood pressure decreased by 10.6 mm. Gt; Art. (3.6 mm Hg in the placebo group). The waist circumference (OT) after two years of therapy decreased by 5.8 cm (in the group receiving a placebo – 2.9 cm).

Thus, Xenical is an effective drug for treating patients with metabolic syndrome, and a decrease in hyperinsulinemia indicates a pathogenetically justified approach to the treatment of insulin resistance. Data from questionnaires of patients at the 52nd and 104th weeks of treatment indicated that patients receiving Xenical were:

  • More satisfied with treatment
  • More satisfied with the dynamics of their state
  • Less concerned about the fact of being overweight.

In 31% of patients taking Xenical, excessive fat release was observed, and the rate of defecation increased in 20.4% of cases. However, only 0.3% of patients discontinued treatment for this reason. Oily discharge from the rectum was noted in 17.5% of patients at 1.2% in the placebo group. It should be noted that these side effects were the result of excessive consumption of fat and, of course, indicate a high effectiveness of the drug. Xenical should be used with a moderately hypocaloric diet containing 30% of calories in the form of fats. In this case, discomfort from the intestine, as a rule, is not observed.

 

Le rôle de tadalafil (Cialis) dans la rééducation des patients après prostatectomie préservant les filets nerveux

Un nombre croissant de patients atteints d’un cancer de la prostate est actuellement réalisée prostatectomie, et devient donc préservation des nerfs problème particulièrement aigu de leur réadaptation, y compris la restauration d’une érection. Un moyen de traitement de première ligne de la dysfonction érectile chez ces patients sont des inhibiteurs de la phosphodiestérase-5 (PDE-5), en particulier médicament à action prolongée acheter cialis en ligne.

le cancer de la prostate est un problème grave de la médecine moderne. En 2007, il a servi en Russie à la quatrième place (8,9%) au niveau de la maladie et le premier (60%) – sur sa croissance parmi toutes les tumeurs malignes chez les hommes [1]. En même temps, grâce à l’introduction du taux de PSA de dépistage au cours de la dernière décennie a changé de manière significative la structure de la morbidité dans la direction plus tôt, les formes localisées. Cela a conduit au fait qu’un nombre croissant de patients sont maintenant effectué une prostatectomie radicale, y compris la chirurgie préservation des nerfs [2].

La dysfonction érectile après prostatectomie radicale est détermine en grande partie la qualité de vie des patients. Même dans le cas de l’exécution d’opérations de préservation nerveuse dysfonction érectile divers degrés de gravité est observée dans 65-75% des patients [3]. Ceci est particulièrement important pour les patients plus jeunes qui sont plus intéressés à maintenir une érection, qui sont de plus en plus de se porter candidat pour prostatectomie en raison de la détection précoce de la maladie.

Médicaments de première ligne pour la restauration de la fonction érectile après prostatectomie préservant les filets nerveux sont des inhibiteurs de la PDE5, car ils sont assez le plus commode, sûr et efficace chez les patients de ce groupe [2]. Dans une vaste étude récente randomisée multicentrique dans l’exemple vardénafil été montré que les inhibiteurs de la PDE-5 ont été aussi efficaces quel que soit le moment du traitement (immédiatement ou dans un an après la chirurgie) [4].

L’un des médicaments dans ce groupe – Cialis – est apparu en 2003 dans un grand essai randomisé multicentrique, à la réception de la demande après prostatectomie préservant les filets nerveux bilatéral Cialis a amélioré la fonction érectile chez 71% des patients, contre 24% dans le groupe placebo, le pourcentage de rapport sexuel était de 52% à la prise de Cialis et 26%, à savoir, deux fois moins de placebo [5].

Tadalafil, l’ingrédient actif Cialis, la structure chimique différente des deux autres médicaments actuellement utilisés de ce groupe (sildénafil et vardénafil). La vitesse et l’ampleur de l’absorption du tadalafil dans le tractus gastro-intestinal ne dépend pas de la prise de nourriture et de l’alcool. Son temps de demi-vie était de 17,5 heures, alors que le sildénafil et le vardénafil, il est égal à 4-5 h. La réalisation à la fois uniques et multiples érections après la prise de Cialis possible dans les 36 heures [6]. Cela vous permet de prendre le médicament non seulement immédiatement avant les rapports sexuels, mais aussi devant lui.

Durée des concentrations d’action et de la persistance tadalafil dans le sang sont également l’occasion de prendre Cialis sur une base quotidienne, non seulement sur demande. Merci à ces caractéristiques Cialis est un médicament de choix dans des situations où il est difficile de prédire l’heure exacte des rapports sexuels, ainsi que la fréquence des rapports deux fois par semaine ou plus. Dans certains cas, ces caractéristiques contribuent patients tadalafil une plus grande certitude et moins leurs craintes au sujet du temps écoulé depuis le moment de l’ingestion. Ceci est également confirmé par les recherches existantes sur le choix d’un inhibiteur de la PDE5, dans la majorité des patients qui ont préféré est Cialis [7-11].

Le médicament est administré à une dose de 20 mg pas plus d’une fois par jour. Les effets secondaires lors de la prise de Cialis généralement modérément exprimé et les réceptions subséquentes sont réduits ou disparaissent. Parmi eux le diagnostic des maux de tête et dyspepsie. Encore plus rare sont les maux de dos, myalgie, des étourdissements, la congestion nasale. Dans les essais cliniques, le nombre de patients cesser de prendre Cialis en raison des effets secondaires était le même que le nombre a renoncé à un placebo [12]. Comme cela est le cas avec d’autres inhibiteurs de la PDE5, Cialis ne doit pas être pris en même temps que les nitrates, il ne devrait pas y être utilisé par les patients atteints de maladies cardiaques et cardio-vasculaires, qui est contre-exercice.

Par conséquent, Cialis est un moyen pratique et efficace pour le traitement de la dysfonction érectile, même dans un groupe complexe de patients que les patients ayant subi une prostatectomie nerveuse. Il a tous les avantages des inhibiteurs de la PDE-5, mais en raison des particularités de pharmacodynamie permet d’étendre le temps et le mode d’administration du médicament, donnant aux patients une plus grande liberté de choix et la confiance dans le résultat.

A propos de Cialis

Cialis – un médicament qui a longtemps gagné en popularité parmi les hommes qui ont l’érection faible ou instable. Ce fut une énorme quantité d’études et des essais cliniques, impliquant plusieurs milliers de personnes souffrant de dysfonction érectile. L’efficacité du médicament était de 81%, c’est le pourcentage d’hommes a pu rétablir complètement érections « normales », d’autres se sont débarrassés de leurs maux, selon le degré de complexité de la maladie. D’accord, cela est un excellent résultat!

La principale caractéristique est la possibilité de restaurer l’érection Cialis pendant 36 heures après administration du comprimé, ce qui ne se produit que lors de l’excitation sexuelle. Cela permet à des partenaires ne règlent pas un certain temps d’action du médicament et mener une vie normale avant la montée des désirs naturels. En outre, l’efficacité du médicament n’affectera pas un dîner copieux ou bu de l’alcool, qui est aussi un atout certain pour les hommes de tout âge.

Effet de la drogue

Tout ce que nous comprenons que l’effet principal de l’action de Cialis devrait être une seule – pour augmenter la puissance chez les hommes. C’est ce qui se passe après le traitement, au cours de l’excitation sexuelle: les vaisseaux sanguins du pénis se dilatent, après quoi il pénètre dans un flux sanguin renforcé crée ainsi une érection « normale ». Une nette amélioration de la puissance peut être observée déjà au bout de 20 minutes après l’administration du médicament.

L’utilisation et le dosage

Les comprimés sont utilisés à l’intérieur et se laver avec de l’eau, indépendamment des repas. Délai minimum de rapports putatif doit être de 20 minutes. Dans la plupart des cas, les médecins recommandent la dose de 20 mg. Après cela, pendant 36 heures, vous pourrez à tout moment être pleine préparation sexuelle. Fréquence maximale de l’administration ne doit pas dépasser 1 par jour. Pour les patients âgés Aucune modification de la posologie et l’application n’existe pas.

Recommandations et contre-indications

Assurez-vous de consulter votre médecin avant d’utiliser des pilules de Cialis. Selon vos antécédents médicaux, il déterminera les risques auxquels vous pourriez être exposé après l’application du médicament. Voici les règles les plus importantes à suivre:

  1. Comme toute autre formulation telle action, Cialis contre-indiqué en co-application avec des nitrates (qui sont des médicaments pour le traitement des maladies cardio-vasculaires).
  2. Le corps, qui touche sensible à l’un des composants du médicament, Cialis est strictement contre-indiquée.
  3. Il ne peut pas être appliquée aux personnes de moins de 18 ans.
  4. L’hypertension, l’insuffisance hépatique ou rénale, troubles du cœur – est l’un des plus importants pour contre-indication utilisation de Cialis.

Les effets secondaires et surdosage

Merci à l’expérience bien étudiée de l’utilisation des médicaments, les effets secondaires sont rares. Mais il y a des exceptions aux règles, vous devez donc être préparé pour les symptômes suivants:

  1. Maux de tête faibles
  2. Vertiges et vomissements
  3. Afflux de sang au visage
  4. La congestion nasale

En cas de surdosage, le risque d’obtenir l’un des effets secondaires augmente. , Vous devez donc contacter immédiatement un médecin pour effectuer un traitement symptomatique norme.

What is Avodart

Avodart, otherwise known as dutasteride is a drug used for the treatment of benign prostatic hyperplasia (BPH) a disease that is also known as an enlarged prostrate. Avodart is a member of the class of the drugs referred to as 5-alpha-reductase inhibitors.

The enlargement of the prostate gland is caused by male hormone dihydrotestosterone (DHT). In this situation, the testosterone is converted into DHT by the activities of 5-alpha reductase enzyme. Avodart is used in this situation to prevent the conversion of testosterone into dihydrotestosterone. It does this by shrinking prostrate tissue and prevent further prostate enlargement.

Men with an enlarged prostrate can use Avodart to treat benign prostatic hyperplasia (BPH). This health condition causes difficulty in urinating and may lead to some urine dribbling. Avodart helps to improve urinary flow and can as well lead to reduction in the need for prostate surgery later on.

Avodart was certified and approved for use by Food and Drug Administration (FDA) in 2001. It is manufactured by GlaxoSmithKline. This drug is sometimes given with another drug known as tamsulosin (Flomax) for optimal performance.

Avodart Warning: What You Should Know About Avodart

  • Pregnant Women and Children

Avodart is not meant for use by a child or a woman and they should never take it on any condition. This drug has the ability to be absorbed through the skin; it is therefore advisable for women and children to stay away from handling the capsules. Avodart can lead to birth defect if a woman is exposed to it during pregnancy. On no occasion should a woman who is pregnant or planning to become pregnant in future handle Avodart. A woman or a child that comes in contact with Avodart should immediately wash the area affected immediately with soap and water.

  • Avoid Chewing

Avodart can irritate your mouth, lips or throat if you swallow a broken or an opened capsule. Avoid chewing, opening or crushing this drug. Instead, you should swallow it directly.

  • Cancer Risk

Let your doctor know if you have ever had an allergic reaction to Avodart. This drug may increase the risk of developing prostate cancer. It is important that your doctor perform test to ensure that you do not possess other health conditions that can lead to developing prostate cancer as a result of taking dutasteride.

Avodart Dosage

Dutasteride (Avodart) usually comes in capsules which contains 0.5 milligrams (mg) of dutasteride.

It is highly advisable that you take Avodart as exactly prescribed by your doctor. Avoid taking larger or smaller amount or taking this drug for a longer period than recommended by your doctor. Ensure that you strictly follow the instructions at your prescription label at all times.

Avodart can be taken with or without food. However, avoid crushing, chewing or opening the capsule to avoid irritation of the mouth, lips and throat. Swallow the capsule whole.

Note: Unless your doctor tells you otherwise, avoid taking more than one, 0.5 mg capsule of dutasteride a day.

To preserve Avodart well; store in a room temperature away from heat and moisture. If affected by heat, the capsules may become leaky and soft or even stick together. Avoid using any of the Avodart capsules that is leaking or cracked.

What to do when you miss your dose?

If there is still enough time between your next doses, take the missed dose immediately. However, avoid taking the dose if it is almost time for your next dose.

Note: On no occasion should you take extra medicine to make up for the dose you missed.

Avodart Overdose

Too much of Avodart is very risky. Quickly call an emergency room at 911 if you think you may have taken too much of Avodart. You can as well call your local Poison Help line at 1-800-222-1222.

What To Avoid When Taking Avodart

  • Donating Blood

Traces of Avodart can still remain in your blood during treatment and even 6 months after your treatment. During this period, do not donating blood. It can cause a serious birth defect if a pregnant woman receives it through blood transfusion

  • Alcohol

Avoid taking alcohol when treating yourself with Avodart. Alcohol has the potential to leave you dehydrated and make urinating quite difficult for you. When you have a BPH condition; taking alcohol while treating yourself with Avodart can worsen your symptoms.

  • Grapefruit Juice

Avoid taking grapefruit juice while taking Avodart. The juice reduces the speed the body breaks down Avodart. This could lead to Avodart blood levels to rise to a dangerous level.

Avodart Side Effects

The common Side effects of Avodart includes

  • Reduced sex drive
  • Breast tissue changes
  • Erectile dysfunction
  • Reduced sperm count
  • Decreased amount of semen released during sex

The serious side effects include;

  • Impotence
  • Fast-growing prostrate cancer
  • Allergic reaction to Avodart such as hives and other serious skin reactions
  • Birth defects in male fetuses

There have also been some rare occasions where Avodart causes some side effect such as

  • Dizziness
  • Heart failure
  • Pain and swelling of the testicles

Avodart Interaction

Before taking Avodart, let your doctor know about other drugs you are taking. Whether it is prescription, over-the-counter or just supplements, you doctor must know about it.

Ask your doctor if it is safe to Avodart along with the following drugs;

  • Cimetidine (Tagamet)
  • Imatinib (Gleevec)
  • Nefazodone (Serzone)
  • An antidepressant such as nefazodone
  • Conivaptan (Vaprisol);
  • HIV/AIDS medications, such as tipranavir (Aptivus) and ritonavir (Norvir)

What is Zoloft

Zoloft as a Revolutionary Antidepressant

Zoloft, also known as Sertraline, is an effective antidepressant that is classified as a selective serotonin reuptake inhibitor. The active ingredients of the preparation affect the brain chemicals balancing them, thus, providing a desirable effect. The treatment is commonly recommended for patients suffering from depression, premenstrual dysphoric disorder, anxiety, panic attacks and other disorders. Additionally, Zoloft can be used for other purposes that are not mentioned in the information leaflet.

Safety Concerns: Zoloft Precautions, Contraindications and Drug Interactions 

It is inevitable to see a doctor before starting the medication treatment course, since multiple factors, such as wrong usage, bigger or smaller dose, prolonged duration of the intake and others, may cause severe complications and side effects. Inform your healthcare specialist about all the details concerning your general health condition, medications you are taking and other vital points. Pay exceptional attention to health problems including epilepsy, liver or kidney disorders, bipolar disorder, bleeding issues and other concerns. This information will help to make your treatment course safe and effective.

Do not take Zoloft if you are allergic to its active ingredients or similar drugs. Avoid the preparation administration in case you have used a MAO inhibitor within the last 14 days. People under 18 years old are not allowed to take the drug. Besides, the pharmaceutical is not approved for children suffering from OCD and depression.

How to Use Zoloft Safely without Side Effects 

Take Zoloft according to the instructions and recommendations of your healthcare provider once you wish to benefit from its effect and experience no related complications. Try to administer the preparation at the same time each day. The pills can be used with or without food, though with a full glass of water. Do not stop Zoloft intake even if your symptoms improve, but undergo a full treatment course.

Do not miss the medication doses, though if it happened, take the dose as soon as possible, or skip if the following scheduled one should be taken soon. Call your doctor if you have noticed any side effects. Seek emergency medical assistance in case the symptoms include severe allergic reactions, convulsions, high serotonin level in the organism, low sodium levels, manic episodes, etc.

What is Doxycycline

Doxycycline – Innovative Formula of Antibiotics 

Doxycycline is a revolutionary antibiotic that belongs to a group of tetracyclines, potent to treat diverse infections caused by bacteria. The preparation is recommended mainly for gonorrhea, periodontitis, urinary tract infections, chlamydia and others. Besides, the drug is actively used as a treatment for bumps, blemishes and lesions that are caused by rosacea. However, it does not improve related facial redness. Additionally, some types of Doxycycline are approved to be reliable ways to warn or treat malaria, anthrax and different infections caused by ticks, mites, etc.

Primarily to Doxycycline Intake: Precautions and Contraindications 

Using the medication you should be very careful and concerned about possible complications related to Doxycycline misuse and overuse. Do not administer the drug if you are allergic to its active components or similar pharmaceuticals. Children under 8 years old are not recommended to undergo Doxycycline treatment course.

Talk to your doctor about the medication intake to make sure the treatment course will be completely safe and beneficial. Inform your healthcare provider about other health problems you have, including kidney or liver disease, sulfite allergy, asthma, etc. Besides, provide a full list of other medications, herbal treatments and supplements you are taking to avoid drug interactions and negative consequences.

Recommendations for Use 

Doxycycline should be taken following all the doctor’s recommendations and instructions. Do not take the drug in larger or smaller quantities or longer than necessary. Administer the pill with a full glass of water with or without food. Never crush, break or chew the tablet, swallow it whole. Once you have missed Doxycycline dose, take it when possible, but skip it if the next scheduled one should be taken soon. Medicine overuse can lead to severe side effects.

Possible Doxycycline Side Effects 

As any other pharmaceutical, Doxycycline may cause a range of minor side effects, including vomiting, nausea, itching, skin rashes, diarrhea, etc. However, the symptoms should disappear in a few days. Call your healthcare provider immediately if the symptoms do not improve, but instead aggravate. Seek emergency medical assistance in case of more severe complications, such as fever, blurred vision, watery or bloody diarrhea, chest pain, confusion, reasonless weight gain and others.